Sperm DNA fragmentation tests
Although there is still no total consensus regarding the extent of the impact caused by sperm DNA fragmentation on fertilization, many studies show that a high percentage of fragmentation can lead to problems in the fertilization process and in embryonic development itself, affecting the outcome of ART treatment.
It is for this reason that it is becoming increasingly important to include the assessment of sperm DNA fragmentation as a complementary method of analysis for the spermogram.
Fragmentation assessment can be done using direct and indirect methods, which can vary in cost and complexity. Most direct methods are more complex tests that require highly specialized human resources and equipment. Indirect methods have emerged more recently and are generally simpler but equally effective.
The most appropriate method for assessing sperm DNA fragmentation depends on a number of factors, including method availability, cost, purpose and intended accuracy.
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